E2F4 and E2F5 play an essential role in pocket protein-mediated G1 control.

doi:10.1016/s1097-2765(00)00071-x

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Back to search

Article

E2F4 and E2F5 play an essential role in pocket protein-mediated G1 control.

Molecular cell - 1 Sept 2000

Gaubatz S, Lindeman G J, Ishida S, Jakoi L, Nevins J R, Livingston D M, Rempel R E

Abstract excerpt

E2F transcription factors are major regulators of cell proliferation. The diversity of the E2F family suggests that individual members perform distinct functions in cell cycle control. E2F4 and E2F5 constitute a defined subset of the family. Until now, there has been little understanding of their...

Topics

Alleles
Animals
Carrier Proteins
Cell Survival
Cyclin-Dependent Kinase Inhibitor p16
Cyclin-Dependent Kinase Inhibitor p21
Cyclins
DNA-Binding Proteins
E2F4 Transcription Factor
E2F5 Transcription Factor
Fibroblasts

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

G1 Phase

Gene Expression Regulation, Developmental

Genes, ras

Genotype

Heterozygote

Homozygote

Mice

Source

Open in PubMed

Identifiers

PMID: 11030352
DOI: 10.1016/s1097-2765(00)00071-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-11030352-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

E2F4 and E2F5 play an essential role in pocket protein-mediated G1 control.PMID 11030352Read ↗

Novel functions for the transcription factor E2F4 in development and diseaseSemantic proximity Read ↗

The E2F family: specific functions and overlapping interests.Semantic proximity Read ↗

E2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycle.Semantic proximity Read ↗

The E2F transcription factor 2: What do we know?Semantic proximity Read ↗

Role of E2F in cell cycle control and cancerSemantic proximity Read ↗

The role of E2F4 in adipogenesis is independent of its cell cycle regulatory activity.Semantic proximity Read ↗

Induction of S-Phase Entry by E2F Transcription Factors Depends on Their Nuclear LocalizationSemantic proximity Read ↗

Disruption of calvarial ossification in E2f4 mutant embryos correlates with increased proliferation and progenitor cell populations.Semantic proximity Read ↗

Cell Cycle Genes Are the Evolutionarily Conserved Targets of the E2F4 Transcription FactorSemantic proximity Read ↗

Evolving intricacies and implications of E2F1 regulationSemantic proximity Read ↗

E2F1 and E2F2 determine thresholds for antigen-induced T-cell proliferation and suppress tumorigenesis.Semantic proximity Read ↗

Redeployment of Myc and E2f1-3 drives Rb-deficient cell cycles.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.