Article
E2F4 and E2F5 play an essential role in pocket protein-mediated G1 control.
Molecular cell - 1 Sept 2000
Gaubatz S, Lindeman G J, Ishida S, Jakoi L, Nevins J R, Livingston D M, Rempel R E
Abstract excerpt
E2F transcription factors are major regulators of cell proliferation. The diversity of the E2F family suggests that individual members perform distinct functions in cell cycle control. E2F4 and E2F5 constitute a defined subset of the family. Until now, there has been little understanding of their individual biochemical and biological functions. Here, we report that simultaneous inactivation of E2F4 and E2F5 in...
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