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Article

Pleiotropic effect of somatic mutations in the E2F subunit DP-1 gene in human cancer.

Oncogene - 3 Jul 2014

Munro S, Oppermann U, La Thangue N B

Abstract excerpt

Transcription factor E2F-1 and its interaction with pRb provide a key point of control in cell proliferation. E2F-1 participates in both cell cycle progression and apoptosis, and in cells exists with a DP dimerization partner protein, the most prominent being DP-1. By mining the tumor tissue and...

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Source

Identifiers

PMID: 23934193
DOI: 10.1038/onc.2013.316

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23934193-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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