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Article

Proton exit from the heme-copper oxidase of Escherichia coli.

Proceedings of the National Academy of Sciences of the United States of America - 5 Jan 1999

Puustinen A, Wikström M

Abstract excerpt

Pathways of proton entry have been identified in the proton-translocating heme-copper oxidases, but the proton exit pathway is unknown. Here we report experiments with cytochrome bo3 in Escherichia coli cells that may identify the beginning of the exit pathway. Systematic mutations of arginines 438 and 439 (R481 and R482 in the E. coli enzyme), numbering as in cytochrome aa3 from bovine heart mitochondria, which...

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Identifiers

PMID: 9874767
DOI: 10.1073/pnas.96.1.35
PMCID: PMC15088

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Proton exit from the heme-copper oxidase of Escherichia coli.PMID 9874767Read ↗

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