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Article

The cytochrome ba3 oxygen reductase from Thermus thermophilus uses a single input channel for proton delivery to the active site and for proton pumping.

Proceedings of the National Academy of Sciences of the United States of America - 22 Sept 2009

Chang Hsin-Yang, Hemp James, Chen Ying, Fee James A, Gennis Robert B

Abstract excerpt

The heme-copper oxygen reductases are redox-driven proton pumps that generate a proton motive force in both prokaryotes and mitochondria. These enzymes have been divided into 3 evolutionarily related groups: the A-, B- and C-families. Most experimental work on proton-pumping mechanisms has been performed with members of the A-family. These enzymes require 2 proton input pathways (D- and K-channels) to transfer...

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Identifiers

PMID: 19805275
DOI: 10.1073/pnas.0905264106
PMCID: PMC2752507

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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