Article
Proton pumping by cytochrome oxidase: progress, problems and postulates.
Biochimica et biophysica acta - 12 May 2000
Zaslavsky D, Gennis R B
Abstract excerpt
The current status of our knowledge about the mechanism of proton pumping by cytochrome oxidase is discussed. Significant progress has resulted from the study of site-directed mutants within the proton-conducting pathways of the bacterial oxidases. There appear to be two channels to facilitate proton translocation within the enzyme and they are important at different parts of the catalytic cycle. The use of...
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