Article
Genetic analysis of the yeast NUD1 endo-exonuclease: a role in the repair of DNA double-strand breaks.
Current genetics - 1 Dec 1998
Asefa B, Kauler P, Cournoyer D, Lehnert S, Chow T Y
Abstract excerpt
The deoxyribonucleases (DNases) have been shown genetically to be important in the vital processes of DNA repair and recombination. The NUD1 gene, which codes for an endo-exonuclease of Saccharomyces cerevisiae, was analyzed for its role in the DNA double-strand break (DSB) repair processes. While the nud1 strain is only slightly sensitive to ionizing radiation, expression of the HO-endonuclease to introduce a...
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