Article
Synergistic effect of TRM2/RNC1 and EXO1 in DNA double-strand break repair in Saccharomyces cerevisiae.
Molecular and cellular biochemistry - 1 Oct 2007
Choudhury Sibgat A, Asefa Benyam, Kauler Paul, Chow Terry Y-K
Abstract excerpt
In our recently published study, we provided in vitro as well as in vivo data demonstrating the involvement of TRM2/RNC1 in homologous recombination based repair (HRR) of DNA double strand breaks (DSBs), in support of such claims reported earlier. To further validate its role in DNA DSB processing, our present study revealed that the trm2 single mutant displays higher sensitivity to persistent induction of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
