Article
Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae.
Molecular and cellular biology - 1 May 1996
Moore J K, Haber J E
Abstract excerpt
In Saccharomyces cerevisiae, an HO endonuclease-induced double-strand break can be repaired by at least two pathways of nonhomologous end joining (NHEJ) that closely resemble events in mammalian cells. In one pathway the chromosome ends are degraded to yield deletions with different sizes whose e...
Topics
- Animals
- Base Sequence
- Cell Cycle
- Chromosome Deletion
- Chromosomes, Fungal
- Crosses, Genetic
- DNA Repair
- DNA, Fungal
- Deoxyribonucleases, Type II Site-Specific
- Genotype
- Infertility
- Mammals
- Molecular Sequence Data
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Sequence Homology, Nucleic Acid