Article
Characterization of a novel DNA damage-inducible gene of Saccharomyces cerevisiae, DIN7, which is a structural homolog of the RAD2 and RAD27 DNA repair genes.
Molecular & general genetics : MGG - 27 Feb 1997
Mieczkowski P A, Fikus M U, Ciesla Z
Abstract excerpt
A number of DNA damage-inducible genes (DIN) have been identified in Saccharomyces cerevisiae. In the present study we describe isolation of a novel gene, Din7, the expression of which is induced by exposure of cells to UV light, MMS (methyl methane-sulfonate) or HU (hydoxyurea). The DNA sequence...
Topics
- Amino Acid Sequence
- Base Sequence
- Cell Cycle Proteins
- Checkpoint Kinase 1
- Checkpoint Kinase 2
- Cloning, Molecular
- DNA Damage
- DNA Repair
- DNA, Fungal
- DNA-Binding Proteins
- Endodeoxyribonucleases
- Exodeoxyribonucleases
- Fungal Proteins
- Gene Deletion
- Gene Expression Regulation, Fungal
- Humans
- Hydroxyurea
- Lac Operon