Article
Loss of imprinting of the insulin-like growth factor II gene in mouse hepatocellular carcinoma cell lines.
Molecular carcinogenesis - 1 Dec 1998
Ooasa T, Karasaki H, Kanda H, Nomura K, Kitagawa T, Ogawa K
Abstract excerpt
We investigated expression of insulin-like growth factor II (Igf2) in primary cultured hepatocytes, liver epithelial (LE) cell lines derived from normal hepatocytes, and hepatocellular carcinoma (HCC) cell lines from crosses between C3H/HeJ (C3H) and Mus musculus molossinus mice (MSM). Igf2 mRNA...
Topics
- Alleles
- Animals
- Cell Transformation, Neoplastic
- Cells, Cultured
- Crosses, Genetic
- Exons
- Gene Expression Regulation, Neoplastic
- Genomic Imprinting
- Hybridization, Genetic
- Insulin-Like Growth Factor II
- Liver Neoplasms, Experimental
- Male
- Mice
- Mice, Inbred C3H
- Muridae
- Neoplasm Proteins
- Promoter Regions, Genetic
- RNA, Messenger