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Article

Reactivation of the maternally imprinted IGF2 allele in TGFalpha induced hepatocellular carcinomas in mice.

Oncogene - 15 Jan 1998

Harris T M, Rogler L E, Rogler C E

Abstract excerpt

The Insulin like growth factor 2 (IGF2) gene is expressed in several types of tumors in humans and mice and has been implicated as an important growth factor in tumor progression. IGF2 expression in the TGF alpha transgenic mice was analysed in liver and tumors from animals which also contained one or two functional IGF2 alleles. In a two by two mating experiment using transgenic mice containing either a TGF...

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Share to Carcinoma, Hepatocellular
Share to Genomic Imprinting

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Liver Neoplasms

Share to Mice, Transgenic

Share to Polymerase Chain Reaction

Share to Promoter Regions, Genetic

Source

Identifiers

PMID: 9464538
DOI: 10.1038/sj.onc.1201519

Genes

IGF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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