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Article

Isolation and characterization of novel plasmid-encoded umuC mutants.

Journal of bacteriology - 1 Aug 1994

Woodgate R, Singh M, Kulaeva O I, Frank E G, Levine A S, Koch W H

Abstract excerpt

Most inducible mutagenesis in Escherichia coli is dependent upon the activity of the UmuDC proteins. The role of UmuC in this process is poorly understood, possibly because of the limited number of genetically characterized umuC mutants. To better understand the function of the UmuC protein in mutagenic DNA repair, we have isolated several novel plasmid-encoded umuC mutants. A multicopy plasmid that expressed...

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Identifiers

PMID: 8051014
DOI: 10.1128/jb.176.16.5011-5021.1994
PMCID: PMC196340

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