Article
Presence of the variant mannose-binding lectin alleles associated with slower progression to AIDS. Amsterdam Cohort Study.
AIDS (London, England) - 3 Dec 1998
Maas J, de Roda Husman A M, Brouwer M, Krol A, Coutinho R, Keet I, van Leeuwen R, Schuitemaker H
Abstract excerpt
OBJECTIVE: To examine the association between mannose-binding lectin (MBL) polymorphism and progression to AIDS and death in HIV-1 infection. DESIGN AND METHODS: In 131 HIV-1-infected homosexual seroconverters, survival analyses were performed to determine both the association between MBL genotyp...
Topics
- Acquired Immunodeficiency Syndrome
- Adult
- Alleles
- CD4 Lymphocyte Count
- Carrier Proteins
- Case-Control Studies
- Collectins
- Disease Progression
- Follow-Up Studies
- Genetic Variation
- HIV-1
- Humans