Article
Susceptibility to HIV infection and progression of AIDS in relation to variant alleles of mannose-binding lectin.
Lancet (London, England) - 25 Jan 1997
Garred P, Madsen H O, Balslev U, Hofmann B, Pedersen C, Gerstoft J, Svejgaard A
Abstract excerpt
BACKGROUND: Low serum concentrations of mannose-binding lectin (MBL) are associated with increased susceptibility to recurrent infection. Three variant alleles in the MBL gene (B, C, and D), cause low serum concentrations of the protein. We investigated whether variant alleles of MBL affect susceptibility to infection with HIV and progression of AIDS. METHODS: Between 1983 and 1986, all men who attended two...
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