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Article

An age-dependent association of mannose-binding lectin-2 genetic variants on HIV-1-related disease in children.

The Journal of allergy and clinical immunology - 1 Jul 2008

Singh Kumud K, Lieser Alexis, Ruan Ping K, Fenton Terry, Spector Stephen A

Abstract excerpt

BACKGROUND: Mannose-binding lectin (MBL) is part of the lectin pathway of complement activation against various pathogens; however, its role in innate immune responses against HIV-1 infection in children is unknown. OBJECTIVE: This study evaluated the effects of mannose-binding lectin-2 (MBL2) alleles on HIV-1 disease progression and central nervous system (CNS) impairment in children. METHODS: A cohort of 1037...

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Source

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Identifiers

PMID: 18602571
DOI: 10.1016/j.jaci.2008.05.025
PMCID: PMC2748310

Genes

MBL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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