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Mutation studies in lacI transgenic mice after exposure to radiation or cyclophosphamide.

Mutagenesis - 1 Nov 1998

Hoyes K P, Wadeson P J, Sharma H L, Hendry J H, Morris I D

Abstract excerpt

We have used the Big Blue lacI transgenic mouse reporter system to investigate mutation induction in the testes, spleen and liver after exposure to an internally incorporated radionuclide, 114mIn, whole body irradiation with 60Co gamma-rays and systemically administered cyclophosphamide. Spontaneous mutation frequencies were 6-17x10(-6). No statistically significant mutation induction was observed in testes or...

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Identifiers

PMID: 9862192
DOI: 10.1093/mutage/13.6.607

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Mutation studies in lacI transgenic mice after exposure to radiation or cyclophosphamide.PMID 9862192Read ↗

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