Mutation studies in lacI transgenic mice after exposure to radiation or cyclophosphamide.

doi:10.1093/mutage/13.6.607

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Article

Mutation studies in lacI transgenic mice after exposure to radiation or cyclophosphamide.

Mutagenesis - 1 Nov 1998

Hoyes K P, Wadeson P J, Sharma H L, Hendry J H, Morris I D

Abstract excerpt

We have used the Big Blue lacI transgenic mouse reporter system to investigate mutation induction in the testes, spleen and liver after exposure to an internally incorporated radionuclide, 114mIn, whole body irradiation with 60Co gamma-rays and systemically administered cyclophosphamide. Spontane...

Topics

Animals
Bacterial Proteins
Cyclophosphamide
Dose-Response Relationship, Drug
Dose-Response Relationship, Radiation
Escherichia coli Proteins
Indium Radioisotopes
Lac Repressors
Liver
Male
Mice
Mice, Inbred C57BL

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Transgenic

Mutagenicity Tests

Mutagens

Mutation

Repressor Proteins

Spleen

Source

Open in PubMed

Identifiers

PMID: 9862192
DOI: 10.1093/mutage/13.6.607

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9862192-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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