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Article

Comparative analysis of DNA mutations in lacI transgenic mice with age.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 May 1994

Lee A T, DeSimone C, Cerami A, Bucala R

Abstract excerpt

Transgenic mice have been developed recently that contain copies of the well-defined mutagenesis reporter gene, lacI, in an integrated bacteriophage-based shuttle vector. The lacI gene, which is present in all cells of the mouse, can be excised specifically from isolated genomic DNA and efficient...

Topics

Aging
Animals
Bacterial Proteins
Base Sequence
DNA
Escherichia coli Proteins
Lac Repressors
Male
Mice
Mice, Inbred C57BL
Mice, Transgenic
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Repressor Proteins

Sequence Analysis

Source

Identifiers

PMID: 8181674
DOI: 10.1096/fasebj.8.8.8181674

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8181674-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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