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Article

Comparative analysis of DNA mutations in lacI transgenic mice with age.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 May 1994

Lee A T, DeSimone C, Cerami A, Bucala R

Abstract excerpt

Transgenic mice have been developed recently that contain copies of the well-defined mutagenesis reporter gene, lacI, in an integrated bacteriophage-based shuttle vector. The lacI gene, which is present in all cells of the mouse, can be excised specifically from isolated genomic DNA and efficiently packaged into bacteriophage particles after the addition of packaging extracts. Mutations of the lacI gene are...

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PMID: 8181674
DOI: 10.1096/fasebj.8.8.8181674

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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