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Article

Genetic analysis of PHIP intestinal mutations in MutaMouse.

Mutagenesis - 1 Nov 1998

Lynch A M, Gooderham N J, Davies D S, Boobis A R

Abstract excerpt

The mutagenicity of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) was investigated in male MutaMouse mice administered 20 mg/kg per o.s. for 4 days and killed 7 days later. Genomic DNA was extracted from liver, kidney and small and large intestine and the mutation frequency (MF) at the lacZ locus was determined using a positive selection assay. Mutant lacZ clones from the intestine were characterized...

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Source

Identifiers

PMID: 9862191
DOI: 10.1093/mutage/13.6.601

Genes

DHFR
PHIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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