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Article

The lacI gene as a target for mutation in transgenic rodents and Escherichia coli.

Genetics - 1 Apr 1998

de Boer J G, Glickman B W

Abstract excerpt

The lacI gene has been used extensively for the recovery and analysis of mutations in bacteria with various DNA repair backgrounds and after exposure to a wide variety of mutagens. This has resulted in a large database of information on mutational mechanisms and specificity of many mutagens, as well as the effect of DNA repair background on mutagenicity. Most importantly, knowledge about the mutational...

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Identifiers

PMID: 9560364
DOI: 10.1093/genetics/148.4.1441
PMCID: PMC1460077

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