The lacI gene as a target for mutation in transgenic rodents and Escherichia coli.

doi:10.1093/genetics/148.4.1441

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Article

The lacI gene as a target for mutation in transgenic rodents and Escherichia coli.

Genetics - 1 Apr 1998

de Boer J G, Glickman B W

Abstract excerpt

The lacI gene has been used extensively for the recovery and analysis of mutations in bacteria with various DNA repair backgrounds and after exposure to a wide variety of mutagens. This has resulted in a large database of information on mutational mechanisms and specificity of many mutagens, as w...

Topics

Amino Acid Sequence
Animals
Animals, Genetically Modified
Bacterial Proteins
Base Sequence
Color
DNA
DNA Methylation
Escherichia coli
Escherichia coli Proteins
Humans
Lac Repressors
Molecular Sequence Data
Mutation
Repressor Proteins
Rodentia
Sequence Deletion
Viral Plaque Assay

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