Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Use of chromosome substitution strains to identify seizure susceptibility loci in mice.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jan 2007

Winawer Melodie R, Kuperman Rachel, Niethammer Martin, Sherman Steven, Rabinowitz Daniel, Guell Irene Plana, Ponder Christine A, Palmer Abraham A

Abstract excerpt

Seizure susceptibility varies among inbred mouse strains. Chromosome substitution strains (CSS), in which a single chromosome from one inbred strain (donor) has been transferred onto a second strain (host) by repeated backcrossing, may be used to identify quantitative trait loci (QTLs) that contribute to seizure susceptibility. QTLs for susceptibility to pilocarpine-induced seizures, a model of temporal lobe...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes
Share to Genetic Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Inbred A

Share to Mice, Inbred Strains

Share to Quantitative Trait Loci

Share to Seizures

Share to Species Specificity

Source

Open in PubMed Open full text

Identifiers

PMID: 17242861
DOI: 10.1007/s00335-006-0087-6
PMCID: PMC2640942

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Use of chromosome substitution strains to identify seizure susceptibility loci in mice.PMID 17242861Read ↗

Phenotyping mouse chromosome substitution strains reveal multiple QTLs for febrile seizure susceptibility.Semantic proximity Read ↗

Mapping a mouse limbic seizure susceptibility locus on chromosome 10.Semantic proximity Read ↗

Generation and characterization of pilocarpine-sensitive C57BL/6 mice as a model of temporal lobe epilepsy.Semantic proximity Read ↗

A locus on mouse Ch10 influences susceptibility to limbic seizure severity: fine mapping and in silico candidate gene analysis.Semantic proximity Read ↗

Differences in sensitivity to the convulsant pilocarpine in substrains and sublines of C57BL/6 mice.Semantic proximity Read ↗

Genetic dissection of complex traits with chromosome substitution strains of mice.Semantic proximity Read ↗

Collaborative Cross mice reveal extreme epilepsy phenotypes and genetic loci for seizure susceptibility.Semantic proximity Read ↗

Mapping murine loci for seizure response to kainic acid.Semantic proximity Read ↗

Chromosome substitution strains: some quantitative considerations for genome scans and fine mapping.Semantic proximity Read ↗

Quantitative trait loci for electrical seizure threshold mapped in C57BLKS/J and C57BL/10SnJ mice.Semantic proximity Read ↗

Genomic survey of prepulse inhibition in mouse chromosome substitution strains.Semantic proximity Read ↗

Segregation of Seizure Traits in C57 Black Mouse Substrains Using the Repeated-Flurothyl ModelSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.