Genetic association of a GABA(A) receptor gamma2 subunit variant with severity of acute physiological dependence on alcohol.

doi:10.1007/s003359900909

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Article

Genetic association of a GABA(A) receptor gamma2 subunit variant with severity of acute physiological dependence on alcohol.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Dec 1998

Buck K J, Hood H M

Abstract excerpt

The ultimate goal of quantitative trait locus (QTL) mapping is to identify the genes affecting complex traits. Using animal models, we recently identified QTLs on mouse Chromosomes (Chrs) 1, 4, and 11 affecting genetic predisposition to acute alcohol withdrawal. Among mice derived from the C57BL/...

Topics

Animals
Central Nervous System Depressants
Chromosomes
DNA, Complementary
Ethanol
Female
Genetic Predisposition to Disease
Genetic Variation
Male
Mice
Mice, Inbred C57BL
Mice, Inbred DBA
Mice, Inbred Strains
Polymorphism, Genetic
Pregnancy
Quantitative Trait, Heritable
Receptors, GABA-A
Recombination, Genetic

Source

Open in PubMed

Identifiers

PMID: 9880662
DOI: 10.1007/s003359900909

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9880662-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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