Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic association of a GABA(A) receptor gamma2 subunit variant with severity of acute physiological dependence on alcohol.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Dec 1998

Buck K J, Hood H M

Abstract excerpt

The ultimate goal of quantitative trait locus (QTL) mapping is to identify the genes affecting complex traits. Using animal models, we recently identified QTLs on mouse Chromosomes (Chrs) 1, 4, and 11 affecting genetic predisposition to acute alcohol withdrawal. Among mice derived from the C57BL/6J (B6) and DBA/2J (D2) inbred strains, the locus identified on Chr 11 ( approximately 20 cM) accounted for 12% of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA, Complementary
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Variation

Share to Mice, Inbred C57BL

Share to Polymorphism, Genetic

Share to Pregnancy

Share to Recombination, Genetic

Source

Identifiers

PMID: 9880662
DOI: 10.1007/s003359900909

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic association of a GABA(A) receptor gamma2 subunit variant with severity of acute physiological dependence on alcohol.PMID 9880662Read ↗

Allelic variation in the GABA A receptor gamma2 subunit is associated with genetic susceptibility to ethanol-induced motor incoordination and hypothermia, conditioned taste aversion, and withdrawal in BXD/Ty recombinant inbred mice.Semantic proximity Read ↗

Quantitative Trait Loci Involved in Genetic Predisposition to Acute Alcohol Withdrawal in MiceSemantic proximity Read ↗

Association analysis of sequence variants of GABA(A) alpha6, beta2, and gamma2 gene cluster and alcohol dependence.Semantic proximity Read ↗

Association Analysis of Sequence Variants of the GABAAα6, β2, and γ2 Gene Cluster and Alcohol DependenceSemantic proximity Read ↗

Use of recombinant inbred strains for studying genetic determinants of responses to alcohol.Semantic proximity Read ↗

A systems genetic analysis of alcohol drinking by mice, rats and men: influence of brain GABAergic transmission.Semantic proximity Read ↗

Genetic variation in GABRβ1 and the risk for developing alcohol dependence.Semantic proximity Read ↗

Genetics of ethanol-induced locomotor activation: detection of QTLs in a C57BL/6J x DBA/2J F2 intercross.Semantic proximity Read ↗

Human gamma-aminobutyric acid A receptor alpha2 gene moderates the acute effects of alcohol and brain mRNA expression.Semantic proximity Read ↗

Atp1a2 and Kcnj9 are candidate genes underlying sensitivity to oxycodone-induced locomotor activation and withdrawal-induced anxiety-like behaviors in C57BL/6 substrainsSemantic proximity Read ↗

GABAA receptor beta 1, beta 2, and beta 3 subunits: comparisons in DBA/2J and C57BL/6J mice.Semantic proximity Read ↗

Ethanol tolerance and withdrawal responses in GABA(A) receptor alpha 6 subunit null allele mice and in inbred C57BL/6J and strain 129/SvJ mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.