Article
Plasticity of the neoplastic phenotype in vivo is regulated by epigenetic factors.
Proceedings of the National Academy of Sciences of the United States of America - 22 Dec 1998
McCullough K D, Coleman W B, Ricketts S L, Wilson J W, Smith G J, Grisham J W
Abstract excerpt
Age of host and transplantation-site microenvironment influence the tumorigenic potential of neoplastically transformed liver epithelial cells. Tumorigenic BAG2-GN6TF rat liver epithelial cells consistently form tumors at ectopic sites, but differentially express tumorigenicity or hepatocytic dif...
Topics
- Aging
- Animals
- Cell Division
- Cell Line
- Cell Transformation, Neoplastic
- Cells, Cultured
- Liver
- Liver Neoplasms, Experimental
- Liver Transplantation
- Male
- Phenotype
- Postoperative Complications
- Rats
- Rats, Inbred F344