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Article

Plasticity of the neoplastic phenotype in vivo is regulated by epigenetic factors.

Proceedings of the National Academy of Sciences of the United States of America - 22 Dec 1998

McCullough K D, Coleman W B, Ricketts S L, Wilson J W, Smith G J, Grisham J W

Abstract excerpt

Age of host and transplantation-site microenvironment influence the tumorigenic potential of neoplastically transformed liver epithelial cells. Tumorigenic BAG2-GN6TF rat liver epithelial cells consistently form tumors at ectopic sites, but differentially express tumorigenicity or hepatocytic differentiation in the liver depending on host age and route of cell transplantation into the liver. Direct inoculation...

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Identifiers

PMID: 9860969
DOI: 10.1073/pnas.95.26.15333
PMCID: PMC28043

Genes

BAG2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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