Comparison of hepatocyte phenotypes at the glutathione transferase and albumin loci in Sprague-Dawley and Nagase analbuminemic rats and F1 progeny after initiation and promotion.

doi:10.1093/carcin/14.7.1313

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Article

Comparison of hepatocyte phenotypes at the glutathione transferase and albumin loci in Sprague-Dawley and Nagase analbuminemic rats and F1 progeny after initiation and promotion.

Carcinogenesis - 1 Jul 1993

Dragan Y P, Peterson J, Pitot H C

Abstract excerpt

Hepatocarcinogenesis was examined in an initiation--promotion protocol with a single initiating dose of 7,12-dimethylbenz[a]anthracene (DMBA) followed by promotion with phenobarbital (PB) in the Nagase analbuminemic rat (NA), the Sprague-Dawley rat (SD) and their F1 crosses. All rats received a 7...

Topics

9,10-Dimethyl-1,2-benzanthracene
Albumins
Animals
Female
Glutathione Transferase
Liver
Liver Neoplasms, Experimental
Male
Phenobarbital
Phenotype
Precancerous Conditions
Rats
Rats, Mutant Strains
Rats, Sprague-Dawley

Source

Open in PubMed

Identifiers

PMID: 8330343
DOI: 10.1093/carcin/14.7.1313

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8330343-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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