Article
Spontaneous neoplastic transformation of WB-F344 rat liver epithelial cells.
The American journal of pathology - 1 Dec 1998
Hooth M J, Coleman W B, Presnell S C, Borchert K M, Grisham J W, Smith G J
Abstract excerpt
Several studies have shown that cultured rat liver epithelial cells transform spontaneously after chronic maintenance in a confluent state in vitro. In the present study, multiple independent lineages of low-passage WB-F344 rat liver epithelial stem-like cells were initiated and subjected in para...
Topics
- Animals
- Cell Transformation, Neoplastic
- Cell Transplantation
- Cells, Cultured
- Clone Cells
- Epithelial Cells
- Liver
- Liver Neoplasms
- Microscopy, Electron
- Neoplasm Transplantation
- Phenotype
- Rats
