Article
Transgenic hepatocarcinogenesis in the rat.
The American journal of pathology - 1 Aug 1994
Hully J R, Su Y, Lohse J K, Griep A E, Sattler C A, Haas M J, Dragan Y, Peterson J, Neveu M, Pitot H C
Abstract excerpt
Although transgenic hepatocarcinogenesis has been accomplished in the mouse with a number of genetic constructs targeting the oncogene to expression primarily in the liver, no example of this process has yet been developed in the rat. Because our understanding of the multistage nature of hepatoca...
Topics
- Animals
- Animals, Genetically Modified
- Animals, Newborn
- Biomarkers, Tumor
- Liver
- Liver Neoplasms, Experimental
- Phenotype
- Rats