Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transgenic hepatocarcinogenesis in the rat.

The American journal of pathology - 1 Aug 1994

Hully J R, Su Y, Lohse J K, Griep A E, Sattler C A, Haas M J, Dragan Y, Peterson J, Neveu M, Pitot H C

Abstract excerpt

Although transgenic hepatocarcinogenesis has been accomplished in the mouse with a number of genetic constructs targeting the oncogene to expression primarily in the liver, no example of this process has yet been developed in the rat. Because our understanding of the multistage nature of hepatocarcinogenesis is most advanced in the rat, we have developed a strain of transgenic rats carrying the promoter-enhancer...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Newborn
Share to Biomarkers, Tumor
Share to Animals, Genetically Modified

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Liver Neoplasms, Experimental

Share to Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 8053496
PMCID: PMC1887380

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transgenic hepatocarcinogenesis in the rat.PMID 8053496Read ↗

Conditional liver-specific expression of simian virus 40 T antigen leads to regulatable development of hepatic neoplasm in transgenic mice.Semantic proximity Read ↗

Pulmonary carcinogenesis in transgenic mice.Semantic proximity Read ↗

A transgenic mouse model of steatosis and hepatocellular carcinoma associated with chronic hepatitis C virus infection in humans.Semantic proximity Read ↗

Transgenic mouse models of hepatitis B virus‐associated hepatocellular carcinomaSemantic proximity Read ↗

Transgenic models for detection of mutations in tumors and normal tissues of rodents.Semantic proximity Read ↗

Steatosis and liver cancer in transgenic mice expressing the structural and nonstructural proteins of hepatitis C virus.Semantic proximity Read ↗

CRISPR/Cas9-mediated p53 and Pten dual mutation accelerates hepatocarcinogenesis in adult hepatitis B virus transgenic mice.Semantic proximity Read ↗

Hepatocellular alterations and dysregulation of oncogenic pathways in the liver of transgenic mice overexpressing growth hormoneSemantic proximity Read ↗

Hepatitis C virus core protein induces hepatic steatosis in transgenic mice.Semantic proximity Read ↗

Applications of transgenic and knockout mice in alcohol research.Semantic proximity Read ↗

Transgenic animal models in toxicology: historical perspectives and future outlook.Semantic proximity Read ↗

Molecular basis for the synergy between alcohol and hepatitis C virus in hepatocarcinogenesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.