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Article

Polymorphism within the promoter of the serotonin transporter gene and antidepressant efficacy of fluvoxamine.

Molecular psychiatry - 1 Nov 1998

Smeraldi E, Zanardi R, Benedetti F, Di Bella D, Perez J, Catalano M

Abstract excerpt

Depression with psychotic features has been shown to respond to selective serotonin reuptake inhibitors (SSRIs). The serotonin transporter (5-HTT) is a prime target for SSRIs. A functional polymorphism within the promoter region of the 5-HTT gene, leading to different transcriptional efficiency, was recently reported. We tested the hypothesis that allelic variation of the 5-HTT promoter could be related to the...

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Source

Identifiers

PMID: 9857976
DOI: 10.1038/sj.mp.4000425

Genes

HTT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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