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Article

Influence of monoamine oxidase A and serotonin receptor 2A polymorphisms in SSRI antidepressant activity.

The international journal of neuropsychopharmacology - 1 Mar 2002

Cusin Cristina, Serretti Alessandro, Zanardi Raffaella, Lattuada Enrico, Rossini David, Lilli Roberta, Lorenzi Cristina, Smeraldi Enrico

Abstract excerpt

The aim of the present study was to test a possible effect of the monoamine oxidase A (MAOA) and serotonin receptor 2A (5-HT-2A) gene variants on the antidepressant activity of fluvoxamine and paroxetine in a sample of major (n = 248) and bipolar (n = 195) depressives, with or without psychotic features. A total of 443 in-patients were treated with 300 mg fluvoxamine (n = 307) or 20-40 mg paroxetine (n = 136) for...

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Source

Identifiers

PMID: 12057029
DOI: 10.1017/S1461145701002711

Genes

MAOA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Influence of monoamine oxidase A and serotonin receptor 2A polymorphisms in SSRI antidepressant activity.PMID 12057029Read ↗

Influence of tryptophan hydroxylase and serotonin transporter genes on fluvoxamine antidepressant activity.Semantic proximity Read ↗

The C(-1019)G polymorphism of the 5-HT1A gene promoter and antidepressant response in mood disorders: preliminary findings.Semantic proximity Read ↗

Monoamine oxidase A variant influences antidepressant treatment response in female patients with Major Depression.Semantic proximity Read ↗

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A monoamine oxidase B gene variant and short-term antidepressant treatment response.Semantic proximity Read ↗

Genetic variation in the 5-HT5A receptor gene in patients with bipolar disorder and major depression.Semantic proximity Read ↗

Serotonin transporter polymorphisms and side effects in antidepressant therapy--a pilot study.Semantic proximity Read ↗

Association study of a monoamine oxidase a gene promoter polymorphism with major depressive disorder and antidepressant response.Semantic proximity Read ↗

Association analysis between a functional polymorphism in the monoamine oxidase A gene promoter and severe mood disorders.Semantic proximity Read ↗

Serotonin-2A-receptor and -transporter polymorphisms: lack of association in patients with major depression.Semantic proximity Read ↗

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