Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Antipanic efficacy of paroxetine and polymorphism within the promoter of the serotonin transporter gene.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Dec 2005

Perna Giampaolo, Favaron Elisa, Di Bella Daniela, Bussi Riccardo, Bellodi Laura

Abstract excerpt

Serotonin selective reuptake inhibitors (SSRIs) are the drugs of choice in the treatment of panic disorder (PD). The serotonin transporter (5-HTT) is a prime target for SSRIs. A functional polymorphism within the promoter region of the 5-HTT gene, leading to different transcriptional efficiency,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antidepressive Agents, Second-Generation
Share to Fear
Share to Panic Disorder

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Paroxetine

Share to Psychiatric Status Rating Scales

Share to Reverse Transcriptase Polymerase Chain Reaction

Share to Serotonin Plasma Membrane Transport Proteins

Share to Surveys and Questionnaires

Source

Identifiers

PMID: 16034444
DOI: 10.1038/sj.npp.1300822

Genes

HTT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16034444-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Antipanic efficacy of paroxetine and polymorphism within the promoter of the serotonin transporter gene.PMID 16034444Read ↗

Genetic variation in the serotonin transporter promoter region affects serotonin uptake in human blood platelets.Semantic proximity Read ↗

The association between serotonin-related gene polymorphisms and susceptibility and early sertraline response in patients with panic disorder.Semantic proximity Read ↗

The association between serotonin-related gene polymorphisms and susceptibility and early sertraline response in patients with panic disorderSemantic proximity Read ↗

Serotonin transporter gene regulatory region polymorphism (5-HTTLPR), [3H]paroxetine binding in healthy control subjects and alcohol-dependent patients and their relationships to impulsivity.Semantic proximity Read ↗

Polymorphisms in the serotonin receptor gene HTR2A are associated with quantitative traits in panic disorder.Semantic proximity Read ↗

Meta-analysis argues for a female-specific role of MAOA-uVNTR in panic disorder in four European populations.Semantic proximity Read ↗

An association study between a transcriptional polymorphism in the serotonin transporter gene and panic disorder in a Japanese population.Semantic proximity Read ↗

Determinants of pharmacodynamic trajectory of the therapeutic response to paroxetine in Japanese patients with panic disorder.Semantic proximity Read ↗

Excess of high activity monoamine oxidase A gene promoter alleles in female patients with panic disorder.Semantic proximity Read ↗

Associations between serotonin-related gene polymorphisms and panic disorder.Semantic proximity Read ↗

The short/long polymorphism in the serotonin transporter gene promoter is not associated with panic disorder in a Scandinavian sample.Semantic proximity Read ↗

Serotonin transporter gene polymorphism (5-HTTLPR) in patients with oral lichen planus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.