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Article

Influence of tryptophan hydroxylase and serotonin transporter genes on fluvoxamine antidepressant activity.

Molecular psychiatry - 1 Sept 2001

Serretti A, Zanardi R, Rossini D, Cusin C, Lilli R, Smeraldi E

Abstract excerpt

The aim of the present study was to test a possible effect of the A218C tryptophan hydroxylase (TPH) gene variant on the antidepressant activity of fluvoxamine in a sample of major and bipolar depressives, with or without psychotic features. Two hundred and seventeen inpatients were treated with fluvoxamine 300 mg and either placebo or pindolol in a double blind design for 6 weeks. The severity of depressive...

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Source

Identifiers

PMID: 11526473
DOI: 10.1038/sj.mp.4000876

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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