Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The C(-1019)G polymorphism of the 5-HT1A gene promoter and antidepressant response in mood disorders: preliminary findings.

The international journal of neuropsychopharmacology - 1 Dec 2004

Serretti Alessandro, Artioli Paola, Lorenzi Cristina, Pirovano Adele, Tubazio Viviana, Zanardi Raffaella

Abstract excerpt

Several studies have demonstrated the involvement of 5-HT1A receptors in the pathogenesis of depression and in the antidepressant response to SSRIs. A functional new variant in the promoter region of the 5-HT1A gene was recently reported (-1019 C>G). The aim of this study is to investigate a possible association between this 5-HT1A receptor variant and antidepressant response to fluvoxamine in a sample of 262...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antidepressive Agents, Second-Generation
Share to DNA

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Fluvoxamine

Share to Genotype

Share to Mood Disorders

Share to Promoter Regions, Genetic

Share to Psychiatric Status Rating Scales

Share to Receptor, Serotonin, 5-HT1A

Source

Identifiers

PMID: 15458611
DOI: 10.1017/S1461145704004687

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The C(-1019)G polymorphism of the 5-HT1A gene promoter and antidepressant response in mood disorders: preliminary findings.PMID 15458611Read ↗

5-HT1A gene variants and psychiatric disorders: a review of current literature and selection of SNPs for future studies.Semantic proximity Read ↗

Association between the 5-HT1A receptor gene polymorphism (rs6295) and antidepressants: a meta-analysis.Semantic proximity Read ↗

Serotonin transporter gene-linked polymorphic region: possible pharmacogenetic implications of rare variants.Semantic proximity Read ↗

Effect of 5-HT1A receptor gene polymorphism on negative and depressive symptom response to antipsychotic treatment of drug-naive psychotic patients.Semantic proximity Read ↗

Human 5-HT1A receptor C(-1019)G polymorphism and psychopathology.Semantic proximity Read ↗

The effects of a 5-hydroxytryptamine 1A receptor gene polymorphism on the clinical response to fluvoxamine in depressed patients.Semantic proximity Read ↗

Response to fluoxetine and serotonin 1A receptor (C-1019G) polymorphism in Taiwan Chinese major depressive disorder.Semantic proximity Read ↗

Beta-1-adrenergic receptor gene in major depression: influence on antidepressant treatment response.Semantic proximity Read ↗

Effect of 5-HT1A gene polymorphisms on antidepressant response in major depressive disorder.Semantic proximity Read ↗

Systematic screening for mutations in the promoter and the coding region of the 5-HT1A gene.Semantic proximity Read ↗

A common C-1018G polymorphism in the human 5-HT1A receptor gene.Semantic proximity Read ↗

Influence of monoamine oxidase A and serotonin receptor 2A polymorphisms in SSRI antidepressant activity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.