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Article

A novel functional polymorphism within the promoter of the serotonin transporter gene: possible role in susceptibility to affective disorders.

Molecular psychiatry - 1 Dec 1996

Collier D A, Stöber G, Li T, Heils A, Catalano M, Di Bella D, Arranz M J, Murray R M, Vallada H P, Bengel D, Müller C R, Roberts G W, Smeraldi E, Kirov G, Sham P, Lesch K P

Abstract excerpt

The serotonin transporter (5-HTT) is a candidate locus for aetiological involvement in affective disorders. Biochemical studies in suicides and depressed patients suggest that 5-HT uptake function is frequently reduced in affective illness. Furthermore, 5-HTT is targeted by widely used antidepres...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9154246

Genes

HTT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-9154246-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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A novel functional polymorphism within the promoter of the serotonin transporter gene: possible role in susceptibility to affective disorders.PMID 9154246Read ↗

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Serotonin transporter 5HTTLPR polymorphism and affective disorders: no evidence of association in a large European multicenter study.Semantic proximity Read ↗

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