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Article

Loss of imprinting and overexpression of IGF2 gene in gastric adenocarcinoma.

Cancer letters - 25 Nov 1997

Wu M S, Wang H P, Lin C C, Sheu J C, Shun C T, Lee W J, Lin J T

Abstract excerpt

Both insulin-like growth factor II (IGF2) and H19 gene are located on chromosome 11p15.5 in close vicinity to each other, and are imprinted on different parental alleles. Although the exact mechanism remains unclear, loss of imprinting (LOI) leading to the biallelic expression of IGF2 and H19 genes has recently been reported in a variety of tumors. To study the role of IGF2 and H19 genes in gastric...

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Source

Identifiers

PMID: 9570380
DOI: 10.1016/s0304-3835(97)00279-6

Genes

IGF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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Loss of imprinting and overexpression of IGF2 gene in gastric adenocarcinoma.PMID 9570380Read ↗

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Loss of imprinting of insulin-like growth factor 2 is associated with increased risk of lymph node metastasis and gastric corpus cancer.Semantic proximity Read ↗

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Alterations in promoter usage and expression levels of insulin-like growth factor-II and H19 genes in cervical carcinoma exhibiting biallelic expression of IGF-II.Semantic proximity Read ↗

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