Monoallelic expression of the insulin-like growth factor-2 gene in ovarian cancer.

Article

Monoallelic expression of the insulin-like growth factor-2 gene in ovarian cancer.

The American journal of pathology - 1 Apr 1996

Yun K, Fukumoto M, Jinno Y

Abstract excerpt

Genomic imprinting is defined as a gamete-specific modification causing differential expression of the two alleles of a gene in somatic cells and is becoming increasingly recognized as playing an important role in a number of human diseases including cancer. We have reported that the loss of the...

Topics

Alleles
Base Sequence
Carcinoma
Female
Gene Expression Regulation, Neoplastic
Humans
Insulin-Like Growth Factor II
Molecular Sequence Data
Ovarian Neoplasms
Ovary

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