Suppression of HIV replication by dominant negative mutants of HIV-1 (review).

doi:10.3892/ijmm.2.3.325

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Article

Suppression of HIV replication by dominant negative mutants of HIV-1 (review).

International journal of molecular medicine - 1 Sept 1998

Inubushi R, Shimano R, Oshima Y, Yoshida K, Kawamura M, Adachi A

Abstract excerpt

Various gag mutants of human immunodeficiency virus type 1 (HIV-1) generated in vitro were evaluated for their potentials to suppress the replication of wild-type (wt) virus. A single-round of wt virus replication in the presence of various mutant proteins was quantitatively monitored by transfec...

Topics

HIV-1
Humans
Mutation
Virus Replication

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