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Article

Unselected mutations in the human immunodeficiency virus type 1 genome are mostly nonsynonymous and often deleterious.

Journal of virology - 1 Mar 2004

Gao Feng, Chen Yalu, Levy David N, Conway Joan A, Kepler Thomas B, Hui Huxiong

Abstract excerpt

Mutation rates of human immunodeficiency virus type 1 (HIV-1) genomes have been estimated using purified reverse transcriptase or single-round infection system. Since small sequences were used as templates, the overall mutation rates could only be extrapolated and the biological significance of mutations is unknown. For direct estimation of HIV-1 mutation rates and understanding of the potential biological...

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Identifiers

PMID: 14963138
DOI: 10.1128/jvi.78.5.2426-2433.2004
PMCID: PMC369203

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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