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Article

Apparent lack of trans-dominant negative effects of various vif mutants on the replication of HIV-1.

Microbes and infection - 1 Oct 2002

Fujita Mikako, Matsumoto Sora, Sakurai Akiko, Doi Naoya, Miyaura Maki, Yoshida Akiko, Adachi Akio

Abstract excerpt

The vif gene of human immunodeficiency virus type 1 (HIV-1) is essential for virus growth in non-permissive cells such as H9. To elucidate the mechanism of action of the Vif protein, vif mutants, which show trans-dominant negative effects on the replication of HIV-1, would be useful tools. In this study, a new assay system to identify the mutants of this category was established. For this new system, various...

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Identifiers

PMID: 12467760
DOI: 10.1016/s1286-4579(02)01646-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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