Article
Suppression of HIV-2 replication by HIV-1 gag mutants.
Biochemical and biophysical research communications - 20 Jul 1998
Shimano R, Inubushi R, Fukumori T, Tamaki M, Oshima Y, Kawamura M, Adachi A
Abstract excerpt
Gag gene mutants of human immunodeficiency virus type 1 (HIV-1) were analyzed for their potentials of inhibiting the replication of wild-type (wt) HIV-2, the second AIDS virus, in a single-round of viral replication. Of twenty-two HIV-1 gag mutants examined, seven were found to efficiently interf...
Topics
- CD4-Positive T-Lymphocytes
- Gene Products, gag
- Genes, Reporter
- Genes, gag
- Genetic Therapy
- HIV Core Protein p24
- HIV-1
- HIV-2
- Humans
- Monocytes
- Mutation
- Suppression, Genetic
- Viral Proteins