Article
Inhibition of HIV/SIV replication by dominant negative Gag mutants.
Virus genes - 1 Jan 1999
Shimano R, Inubushi R, Oshima Y, Adachi A
Abstract excerpt
There are several major strategies against HIV/AIDS. Of these, the gene therapy is a novel, challenging, and promising one. The target genes, which have been extensively studied for the potential gene therapy of HIV/AIDS, include those of cellular and viral origins. Especially, trans-dominant negative Tat, Rev, Env, Pol, and Gag mutants of HIV have currently attracted considerable attention. In this brief review,...
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