Generation and characterization of the human immunodeficiency virus type 1 mutants.

doi:10.1007/BF01310491

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Article

Generation and characterization of the human immunodeficiency virus type 1 mutants.

Archives of virology - 1 Jan 1991

Adachi A, Ono N, Sakai H, Ogawa K, Shibata R, Kiyomasu T, Masuike H, Ueda S

Abstract excerpt

Mutations were introduced by recombinant DNA techniques into 9 genes of an infectious molecular clone of human immunodeficiency virus type 1. The 24 mutants generated were characterized biochemically and biologically by transfection and infection experiments. None of the mutants which have mutati...

Topics

Blotting, Western
DNA, Recombinant
DNA, Viral
Genes, Viral
HIV-1
Mutagenesis
Mutation
RNA-Directed DNA Polymerase
Retroviridae Proteins
Transfection
Virus Replication

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