Article
Phenol sulphotransferase SULT1A1 polymorphism: molecular diagnosis and allele frequencies in Caucasian and African populations.
The Biochemical journal - 1 Jan 1999
Coughtrie M W, Gilissen R A, Shek B, Strange R C, Fryer A A, Jones P W, Bamber D E
Abstract excerpt
Sulphation, catalysed by members of the sulphotransferase (SULT) enzyme family, is an important component of the body's chemical defence mechanism, but also acts to bioactivate mutagens such as hydroxylated aryl and heterocyclic amines. A major human sulphotransferase, SULT1A1 (P-PST), metabolize...
Topics
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Aging
- Alleles
- Arylsulfotransferase
- Base Sequence
- Black People
- Child
- DNA Primers
- Gene Frequency
- Genotype
- Humans
- Middle Aged
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Sulfotransferases