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Article

Linkage of chromosome 5q and 11q gene markers to asthma-associated quantitative traits in Australian children.

American journal of respiratory and critical care medicine - 1 Dec 1998

Palmer L J, Daniels S E, Rye P J, Gibson N A, Tay G K, Cookson W O, Goldblatt J, Burton P R, LeSöuef P N

Abstract excerpt

Asthma is a genetically complex disease, and the investigation of putative linkages to candidate loci in independent populations is an important part of the gene discovery process. This study investigated the linkage of microsatellite markers in the 5q and 11q regions to asthma-associated quantitative traits in 121 Australian Caucasian nuclear families. The families were recruited on the basis of a child proband:...

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Identifiers

PMID: 9847274
DOI: 10.1164/ajrccm.158.6.9804037

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Related research

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Research trail→

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Linkage of chromosome 5q and 11q gene markers to asthma-associated quantitative traits in Australian children.PMID 9847274Read ↗

A genome-wide search for quantitative trait loci underlying asthma.Semantic proximity Read ↗

Meta-analysis for linkage to asthma and atopy in the chromosome 5q31-33 candidate region.Semantic proximity Read ↗

Lack of linkage between chromosome 5q23-33 markers and IgE/bronchial hyperreactivity in 67 Scottish families.Semantic proximity Read ↗

A bivariate Haseman-Elston method and application to the analysis of asthma-related phenotypes on chromosome 5q.Semantic proximity Read ↗

Significant evidence for linkage to chromosome 5q13 in a genome-wide scan for asthma in an extended pedigree resource.Semantic proximity Read ↗

Allelic association of gene markers on chromosomes 5q and 11q with atopy and bronchial hyperresponsiveness.Semantic proximity Read ↗

Improved evidence for linkage on 6p and 5p with retrospective pooling of data from three asthma genome screens.Semantic proximity Read ↗

Pooling data and linkage analysis in the chromosome 5q candidate region for asthma.Semantic proximity Read ↗

Linkage of circulating eosinophils to markers on chromosome 5q.Semantic proximity Read ↗

Quantitative linkage genome scan for atopy in a large collection of Caucasian families.Semantic proximity Read ↗

Linkage analysis of the 5q31-33 candidate region for asthma in 240 UK families.Semantic proximity Read ↗

Absence of genetic linkage of chromosome 5q31 with asthma and atopy in the general population.Semantic proximity Read ↗

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