Article
Absence of genetic linkage of chromosome 5q31 with asthma and atopy in the general population.
Thorax - 1 Sept 1997
Kamitani A, Wong Z Y, Dickson P, van Herwerden L, Raven J, Forbes A B, Abramson M J, Walters E H, Harrap S B
Abstract excerpt
BACKGROUND: Clinical asthma is associated with increased serum total immunoglobulin E (IgE), atopy (skin prick test positivity to common aeroallergens), and bronchial hyperreactivity (BHR) to non-specific stimuli (positive methacholine challenge test). A region on chromosome 5q31-33 has been linked with increased total serum IgE and BHR. A study of the genetic linkage of this region with clinical asthma and atopy...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.