Article
Linkage of circulating eosinophils to markers on chromosome 5q.
American journal of respiratory and critical care medicine - 1 Dec 1998
Martinez F D, Solomon S, Holberg C J, Graves P E, Baldini M, Erickson R P
Abstract excerpt
Although peripheral blood eosinophilia is strongly associated with the risk of developing asthma, genetic determinants of eosinophilia have not been extensively studied. We used sib-pair analysis to assess linkage of circulating eosinophils (as a percent of total white blood cells [WBC]) to nine...
Topics
- Alleles
- Asthma
- Child
- Chromosome Mapping
- Chromosomes, Human, Pair 5
- Confounding Factors, Epidemiologic
- Eosinophilia
- Eosinophils
- Genetic Linkage
- Genetic Markers
- Heterozygote
- Humans
- Immunoglobulin E
- Leukocyte Count
- Linear Models
- Longitudinal Studies
- Odds Ratio
- Reproducibility of Results