Article
Pooling data and linkage analysis in the chromosome 5q candidate region for asthma.
Genetic epidemiology - 1 Jan 2001
Jacobs K B, Burton P R, Iyengar S K, Elston R C, Palmer L J
Abstract excerpt
We investigated a variety of methods for pooling data from eight data sets (n = 5,424 subjects) to validate evidence for linkage of markers in the cytokine cluster on chromosome 5q31-33 to asthma and asthma-associated phenotypes. Chromosome 5 markers were integrated into current genetic linkage and physical maps, and a consensus map was constructed to facilitate effective data pooling. To provide more informative...
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