Article
Improved evidence for linkage on 6p and 5p with retrospective pooling of data from three asthma genome screens.
Genetic epidemiology - 1 Jan 2001
Iyengar S K, Jacobs K B, Palmer L J
Abstract excerpt
To improve our ability to identify genes for complex diseases, evaluation of new methods that retrospectively pool genotype and phenotype data collected by multiple centers is important. Availability of three whole-genome screens enabled us to compare two methods, pooling raw data and meta-analysis. Multipoint linkage analyses were performed on two outcomes, total serum IgE levels and asthma affection status,...
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