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Article

Sepsis-induced lung injury in rats increases alveolar epithelial vulnerability to stretch.

Critical care medicine - 1 Jun 2006

Levine Glenn K, Deutschman Clifford S, Helfaer Mark A, Margulies Susan S

Abstract excerpt

OBJECTIVE: Previous in vitro models have shown that cellular deformation causes dose-dependent injury and death in healthy rat alveolar epithelial cells (AECs). We compared the viability of AECs from septic rats with those from nonseptic rats after 1 hr of cyclic equibiaxial stretch. We hypothesized that sepsis would increase stretch-induced cell death. DESIGN: Laboratory investigation. SETTING: University...

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Source

Identifiers

PMID: 16625134
DOI: 10.1097/01.CCM.0000218813.77367.E2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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