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Article

Divergent functions of CD4+ T lymphocytes in acute liver inflammation and injury after ischemia-reperfusion.

American journal of physiology. Gastrointestinal and liver physiology - 1 Nov 2005

Caldwell Charles C, Okaya Tomohisa, Martignoni Andre, Husted Thomas, Schuster Rebecca, Lentsch Alex B

Abstract excerpt

Hepatic ischemia-reperfusion results in an acute inflammatory response culminating in the recruitment of activated neutrophils that directly injure hepatocytes. Recent evidence suggests that CD4+ lymphocytes may regulate this neutrophil-dependent injury, but the mechanisms by which this occurs remain to be elucidated. In the present study, we sought to determine the type of CD4+ lymphocytes recruited to the liver...

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Source

Identifiers

PMID: 16002566
DOI: 10.1152/ajpgi.00223.2005

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MIP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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