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Article

TCR repertoire evolution during maintenance of CMV-specific T-cell populations.

Immunological reviews - 1 May 2018

Schober Kilian, Buchholz Veit R, Busch Dirk H

Abstract excerpt

During infections and cancer, the composition of the T-cell receptor (TCR) repertoire of antigen-specific CD8+ T cells changes over time. TCR avidity is thought to be a major driver of this process, thereby interacting with several additional regulators of T-cell responses to form a composite immune response architecture. Infections with latent viruses, such as cytomegalovirus (CMV), can lead to large T-cell...

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Identifiers

PMID: 29664573
DOI: 10.1111/imr.12654

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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