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Article

Accumulation of T-Cells with Selected T-Cell Receptors in the Brains of Japanese Encephalitis Virus-Infected Mice

28 Jan 2008

Abstract excerpt

Japanese encephalitis is a severe central nervous system (CNS) disease with a high case fatality rate in humans. We characterized T-cells infiltrating the brain after infection with Japanese encephalitis virus (JEV) in a mouse model and determined the clonality of the infiltrating T-cells by analyzing the sequences of complementary determining region 3 (CDR3) of the T-cell receptor. C3H/He mice died after...

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Identifiers

PMID: 18219133
DOI: 10.7883/yoken.jjid.2008.40

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