Defective modulation of double-strand break repair in ataxia telangiectasia cells by gamma radiation.

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Article

Defective modulation of double-strand break repair in ataxia telangiectasia cells by gamma radiation.

Radiation research - 1 Dec 1998

Sikpi M O, Wang Y, Mallya S M

Abstract excerpt

Ataxia telangiectasia (AT) cells are defective in responding to damage induced by ionizing radiation. To study the modulation of double-strand break (DSB) repair by ionizing radiation and a defect in such modulation in AT cells, we compared processing of linearized shuttle vector pZ189 (linear DN...

Topics

Ataxia Telangiectasia
Ataxia Telangiectasia Mutated Proteins
Base Sequence
Cell Cycle Proteins
Cell Line
Cycloheximide
DNA
DNA Damage
DNA Repair
DNA-Binding Proteins
Gamma Rays
Humans
Lymphocytes
Mutation
Nucleic Acid Conformation
Plasmids
Protein Serine-Threonine Kinases
Protein Synthesis Inhibitors

Source

Open in PubMed

Identifiers

PMID: 9840182

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9840182-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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