Article
Defective modulation of double-strand break repair in ataxia telangiectasia cells by gamma radiation.
Radiation research - 1 Dec 1998
Sikpi M O, Wang Y, Mallya S M
Abstract excerpt
Ataxia telangiectasia (AT) cells are defective in responding to damage induced by ionizing radiation. To study the modulation of double-strand break (DSB) repair by ionizing radiation and a defect in such modulation in AT cells, we compared processing of linearized shuttle vector pZ189 (linear DNA) by unirradiated or gamma-irradiated normal and AT lymphoblast hosts. The linear DNA processed in unirradiated AT and...
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